Eligibility: Inclusion Criteria: 1. Age 18 - 45 years 2. Clinical diagnosis of polycystic ovary syndrome 3. Have a body mass index of 25-35 kg/m 2 4. Absence of pregnancy and breastfeeding 5. No intake of medicine 6. Not willing to get pregnant during the study 7. No presence of chronic infl…

Eligibility: Inclusion Criteria: 1. Age ≥ 18 years. 2. Body mass index ≥ 28 kg/m2 or ≥24kg/m² to \<28 kg/m2 with at least 1 of the following weight-related comorbidities: a) Systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥85 mmHg, or the use of at least one antihypertensive me…

Eligibility: Inclusion Criteria: * parent who identifies as Alaska Native (AN) * parental consent * enrolled in preschool in one of the12 participating Head Start programs * present at school for health screenings Exclusion Criteria: * lack of parental consent * does not have a parent who…

Eligibility: Inclusion Criteria: * Subject is ≥ 18 years of age at the time of the ESG procedure * Subject with a BMI between 30 kg/m2 and 50 kg/m2, inclusive, at the time of the primary ESG procedure using Overstitch Endoscopic Suturing System * Subject completed follow-up 1-year from the E…

Eligibility: Inclusion Criteria: * Obesity, defined as a BMI at or above 2 standard deviations SDs according to the WHO growth reference * Owning a smartphone, needed for video conversations, step counting and the gamification app * Parent consent and child's assent to participate in the pro…

Eligibility: Inclusion Criteria: * Age: 20-80 years * Presence of heart failure * Body-mass index 27 kg/m2 or greater * Stable optimally tolerated dosages of heart failure therapies for 3 months * N-terminal pro B-type natriuretic peptide levels \>350 pg/mL Exclusion Criteria: * Presence o…

Eligibility: Inclusion Criteria: Families Parent or legal caregiver and at least one child aged 5 to 12 years Child identified through electronic health record data from a participating clinical organization Child has had at least one clinical encounter at the participating site within th…

Eligibility: Inclusion Criteria: * • Patient age ranges 18 to 60 years old * Obese patients ; Body mass index(BMI) ≥ 35 - 50 kg/m2 * American Society of Anesthesiologists (ASA) physical status classes II to III * Patients scheduled for laparoscopic bariatric surgery i.e. sleeve gastre…

Eligibility: Pre-inclusion criteria * Man or woman, aged 18 or over, admitted to medical intensive care * Glasgow score = 15 * Patient with acute respiratory failure decompensating COPD and/or having obesity with a body mass index (BMI) greater than 30 * Patient having given free, informed a…

Eligibility: Inclusion Criteria 1. Adults aged 18 years or older. 2. Individuals clinically diagnosed by a physician as having metabolic syndrome (meeting at least three of the following five criteria) or prediabetes: (A) Waist circumference: ≥ 90 cm in men or ≥ 80 cm in women, or body m…

Eligibility: Inclusion Criteria: * BMI \>18 kg/m2 Exclusion Criteria: * Pregnancy, breastfeeding * Diagnosed sleep apnea or AHI \>10 events/hr * Current smoking/Nicotine use * Increased risk of bleeding, pro-coagulant disorders, clotting disorders, anticoagulation therapy * Nerve/neurologi…

Eligibility: Inclusion Criteria: * Signed Informed Consent * A diagnosis of T2DM of ≥6 months, * Hemoglobin A1c (HbA1c) ≥6.5% to ≤10% at Screening * Have a BMI ≥27.0 kg/m2 Exclusion Criteria: * Are currently receiving or planning to receive treatment for diabetic retinopathy and/or macular…

Eligibility: Inclusion Criteria: * Body mass index (BMI) greater than 30 kg/m2, who are eligible for ESG * Patients scheduled to undergo an endoscopic bariatric weight loss procedure (ESG) * Patients older than 18 years and younger than 75 years of age at the time of consent * Patients able…

Eligibility: Inclusion Criteria: 1. Healthy male and female participants, aged 18 to 65 years at the time of screening. 2. Body weight \>50 kg to \<130 kg, and BMI between 22.0 and 45.0 kg/m square. 3. Medically healthy, with no clinically significant abnormalities in medical history, physic…

Eligibility: Inclusion Criteria: * Biological male * BMI 18.5 - 24.9 kg/m2 or \>/= 30 kg/m2 * Body fat \<20% or \>/= 25% * Ability and willingness to engage in an exercise training regimen Exclusion Criteria: * Presence of a chronic health condition, or regular use of associate prescribed…

Eligibility: Eligibility criteria for schools: 1. The principal agrees to accept the randomization process and adhere to the study protocol; 2. The total number of fourth-year students in the school must be more than 50; 3. Schools that have not implemented or plan to implement obesity preve…

Eligibility: Inclusion Criteria: 1. BMI ≥ 30 Kg/m2 or abdominal circumference (waist) \>94 cm in men and \>80 cm in women (IDF criteria for the definition of abdominal obesity) with or without the features that characterize the metabolic syndrome 2. Age range between 18 and 70 years, both se…

Eligibility: Inclusion Criteria: * obese person (class one obesity) * patients with metabolic syndrome * patients with chronic subjective tinnitus (bilateral complaint from more than six months). * older adults aging 65 years and more * both sexes will be included Exclusion Criteria: * res…

Eligibility: Inclusion Criteria: Subject must meet all the inclusion criteria to participate in this study and list each criterion. 1. Age: 21-65 years 2. Patients going for LSG at participating hospitals. 3. Able to provide informed consent Individuals below age 21 would not be recruited…

Eligibility: Inclusion Criteria: * Students from the school * Pediatric from age 6 to 16 * Students from the school that confirmed approval * Signed informed consent by the minor * Signed informed consent by the minor's parents or guardians. Exclusion Criteria: * Presence of HbA1c levels b…