What's being tested:
BEHAVIORAL: Fasted Exercise
BEHAVIORAL: Postprandial Exercise
Eligibility: Inclusion Criteria: 1. Clinical diagnosis of type 1 diabetes for 5 or more years. 2. Treatment using an insulin pump with no change in treatment modality for \> 2 continuous months and willing to share CGM data with the research team. Insulin delivery can be managed using either…
What's being tested:
DRUG: GLP-1 Receptor Agonist
DRUG: Menopausal Hormone Therapy
Eligibility: Individuals fulfilling at enrolment all of the following inclusion criteria are eligible for the study: * Early postmenopausal status (STRAW+10 stage +1b or +1c and FSH\>25.0mU/L) * Presence of menopausal symptoms (total MRS-II score ≥1) * BMI ≥ 27.0kg/m2 * Pre- or existing type…
What's being tested:
DRUG: semaglutide
DRUG: Standard Treatment (Guideline-Based)
Eligibility: Inclusion Criteria: * Age ≥ 18 years. * Diagnosis of T2DM in patients without ASCVD or severe TOD but with SCORE2-Diabetes ≥10% with clinical indication in accordance with current guidelines \[1\] to initiate semaglutide therapy (level of evidence IIa). * Evaluable, pre-randomiz…
What's being tested:
DIETARY_SUPPLEMENT: Beet root juice
DIETARY_SUPPLEMENT: Placebo juice
Eligibility: Inclusion Criteria: Type 2 diabetes Exclusion Criteria: Acute coronary syndrome Vegetarian diet Impaired renal function Absolute indication for proton pump inhibitor Ongoing treatment with organic nitrate Heart failure (ejection fraction \<35%) Any condition that interferes wi…
What's being tested:
DRUG: MTX228
DEVICE: DEXCOM G6
Eligibility: Inclusion Criteria: * clinical diagnosis of T1DM with onset before the age of 35 requiring continuous treatment with insulin within 1 year of diagnosis and the presence of positive T1DM autoantibody titer if diagnosed after age 35 (past or present * HbA1c between 6.0 - 10.0 %. *…
Eligibility: Inclusion criteria * Female or male, aged between ≥ 40 and ≤80 years * Normal LVEF AND absence of akinetic segment assessed by echocardiography (i.e. LVEF≥50%) * Patients diagnosed according to the specific diagnostic criteria of each disease (Cf. table below (definition criteri…
What's being tested:
BEHAVIORAL: Clips Intervention
DEVICE: Structured Questionnaire Only
Eligibility: Inclusion Criteria: * 1\. The diagnosis of gestational diabetes mellitus. * 2\. No any history of disease\* before the pregnancy or do have history of disease\* without taking any medicines. (\*disease, eg. hypertension, diabetes mellitus, hyperthyroidism...etc.) * 3\. No recurr…
What's being tested:
DIETARY_SUPPLEMENT: Wild Blueberry
DIETARY_SUPPLEMENT: Placebo
Eligibility: Inclusion Criteria: * Individuals 45-65 years of age * Diagnosis of elevated blood pressure or stage 1 hypertension (systolic blood pressure = 120-139 mmHg and/or diastolic blood pressure = 80-89 mmHg) for at least 6 months * BMI 25-35 kg/m2 via anthropometric measurements. * Ab…
What's being tested:
DRUG: ZE63-0302
DRUG: Placebo
Eligibility: Inclusion Criteria: 1. Must have given written informed consent before any study-related activities are performed and must be able to understand the full nature and purpose of the study, including possible risks and adverse effects. 2. Adult males and females, ≥18 to ≤65 years o…
What's being tested:
DIAGNOSTIC_TEST: Xylocaine 1%
DIAGNOSTIC_TEST: NaCl 9mg/ml
Eligibility: Inclusion Criteria: * Aged 18 years or older. * Probably diabetic neuropathy confirmed using the Toronto criteria in a "conservative manner", i.e. three out of three symptoms/signs of neuropathy must be present (sensory neuropathy symptoms, distal reduced sensibility, reduced an…
What's being tested:
BEHAVIORAL: Luteal Phase Aerobic Exercise
BEHAVIORAL: Follicular Phase Aerobic Exercise
Eligibility: Inclusion Criteria: * type 1 diabetes diagnosed for at least 1 year * regular menses * using monophasic oral contraceptives * residing in Edmonton, Alberta and able to visit the lab at the University of Alberta Exclusion Criteria: * HbA1c \> 9.9% * frequent and unpredictable h…
What's being tested:
DEVICE: Automated insuling delivery system
Eligibility: Inclusion Criteria (Adults): * Age ≥18 years * Type 1 diabetes ≥3 years * CGM or intermittently scanned CGM (isCGM) use ≥6 months * Approval from the responsible health care provider (HCP) to start AID * Specific AID system chosen ahead of screening after participant has been th…
What's being tested:
DRUG: Definity Suspension for Injection
Eligibility: Inclusion Criteria: * Male or non-pregnant female age 18-65 * Ability and willingness of patient to participate fully in all aspects of this clinical study * Written informed consent obtained and documented Exclusion Criteria: * Excessive body size preventing effective scan of…
What's being tested:
DEVICE: Clinical Demo 2.0
Eligibility: Inclusion Criteria: * Male or female trial participant with clinically diagnosed type 1 or type 2 diabetes for at least 1 year. * Age between 18 and 65 years, both inclusive. * Treated with insulin and/or oral antidiabetic drugs (OADs; type 2 only), multiple dosing insulin thera…
What's being tested:
DRUG: Atherolive
DRUG: Placebo Atherolive
Eligibility: Inclusion Criteria: * Patients over 18 years of age with: * diabetes. Exclusion Criteria: * Exclusion criteria: None.
What's being tested:
DEVICE: Advanced Antibacterial Wound Dressing
DEVICE: Aquacel Ag+ Extra
Eligibility: Inclusion Criteria: * Voluntary, written informed consent obtained prior to any study related activities. * Males and females aged ≥18 years. * DFU(s) present for more than 4 weeks with a maximum diameter of 4 cm. * IWGDF/IDSA Wound infection grades 1 (absent) or 2. * Patients w…
Eligibility: Inclusion Criteria 1. Adults aged 18 years or older. 2. Individuals clinically diagnosed by a physician as having metabolic syndrome (meeting at least three of the following five criteria) or prediabetes: (A) Waist circumference: ≥ 90 cm in men or ≥ 80 cm in women, or body m…
What's being tested:
DRUG: Metformin Hydrochloride
OTHER: placebo
Eligibility: Inclusion Criteria: * ≥12 weeks and ≤5 years postpartum * history of GDM or healthy pregnancy Exclusion Criteria: * prediabetes or diabetes (HbA1c ≥5.7%) * current tobacco use * cardiovascular or metabolic disease * cardiovascular or metabolic medication * history of hypertens…
What's being tested:
DRUG: Aleniglipron
DRUG: Placebo
Eligibility: Inclusion Criteria: * Signed Informed Consent * A diagnosis of T2DM of ≥6 months, * Hemoglobin A1c (HbA1c) ≥6.5% to ≤10% at Screening * Have a BMI ≥27.0 kg/m2 Exclusion Criteria: * Are currently receiving or planning to receive treatment for diabetic retinopathy and/or macular…
Eligibility: Inclusion Criteria: * Adults over the age of 18. * Persons diagnosed with diabetes * Have an email account with access to a reliable internet connection or smartphone Exclusion Criteria: * Minors , ages under 18 * Adults not diagnosed with diabetes * Adults who are unable to p…
Showing 1–20 of 2,032 results
Trial data sourced from
ClinicalTrials.gov (U.S. National Library of Medicine). Data may be delayed. Verify enrollment status directly with the research team.