What's being tested:
DIETARY_SUPPLEMENT: Wild Blueberry
DIETARY_SUPPLEMENT: Placebo
Eligibility: Inclusion Criteria: * Individuals 45-65 years of age * Diagnosis of elevated blood pressure or stage 1 hypertension (systolic blood pressure = 120-139 mmHg and/or diastolic blood pressure = 80-89 mmHg) for at least 6 months * BMI 25-35 kg/m2 via anthropometric measurements. * Ab…
What's being tested:
DRUG: Dextrose 20 % in 500 ML Injection
DRUG: Intralipid
DRUG: Saline
Eligibility: Inclusion Criteria: * Lean: BMI \< 25 kg/m * Normal insulin sensitivity: (calculation based on fasting glucose and insulin concentrations in blood) * Middle-aged: 18-79 years * Blood pressure: \< 140 (systolic) and \< 90 mmHg (diastolic * Weight stable (+/- 5 lbs) for the previo…
What's being tested:
PROCEDURE: Boston keratoprosthesis type 1
PROCEDURE: Glaucoma drainage device
Eligibility: Inclusion Criteria: * Candidate for corneal transplantation due to loss of corneal clarity * Verifiable history of one or more previous full thickness donor corneal transplantation failure * Pre-operative visual acuity of ≤20/80 or worse in the surgical eye * Age ≥18 years * Phy…
What's being tested:
DRUG: Intensive control of SBP and intensive control of LDL-C
DRUG: Intensive control of SBP and standard control of LDL-C
DRUG: Standard control of SBP and intensive control of LDL-C
Eligibility: Inclusion Criteria: * Fulfillment of all of followings 1. At least 19 years old 2. Evidence of CKD defined at least 3 months before and at the time of screening visit with CKD-EPI eGFR ≥15 to \<45 mL/min/1.73 m2 3. SBP of * 130-180 mmHg on 0 or 1 medication * 1…
Eligibility: Inclusion Criteria: * Single pregnancy * Maternal age ≥18 * High risk (≥1/50) in the first-trimester screening for preeclampsia * Gestational age between 11+0 and 16+6 weeks of gestation Exclusion Criteria: * Fetal malformation * Fetal death * Maternal digestive inflammatory d…
What's being tested:
DIAGNOSTIC_TEST: 24 hour blood pressure (BP) monitoring
DIAGNOSTIC_TEST: Polysomnography
Eligibility: Inclusion Criteria: * Subjects diagnosed with no known history of hypertension, diabetes, or sleep disorders. * Self-identify as Somali. * Adult males and females who are older than 18 years of age. Exclusion Criteria: * Anyone under 18 years or over 70 years. * Positive pregn…
What's being tested:
DRUG: SPC 1001 Mid2
DRUG: SPC 2002
DRUG: SPC 2003
Eligibility: Inclusion Criteria: * Men and women aged 19 to 75 years whose blood pressure measured at the screening visit meets the following criteria. Exclusion Criteria: * Patients whose blood pressure measured at the screening and randomization visits meets the criteria of MSSBP ≥180 mm…
What's being tested:
DRUG: Eszopiclone 3 mg
DRUG: Placebo
Eligibility: Inclusion Criteria: * Adults (30 to 75 years-old) * BMI \<40Kg/m2; * Availability to participate * History of HBP under regular treatment (systolic pressure between 130-160 and diastolic pressure between 80-100 mmHg). Exclusion Criteria: * Use of benzodiazepines or "Z" drugs;…
What's being tested:
DRUG: L608 Liposomal inhalation suspension
DRUG: Placebo Solution
Eligibility: Key Inclusion Criteria: 1. Men and women aged between 18 and 65 (inclusive) at the time of Screening visit. 2. Participants with Body Mass Index (BMI) of ≥18.5 and ≤32.0 kg/m2 and weight of at least 50 kg at Screening. 3. Non-smokers or former smokers who have smoked ≤ 100 cigar…
What's being tested:
DRUG: Furosemide 20 Milligrams
Eligibility: Inclusion Criteria: * Men or women over 18 years of age. * Diagnosis of heart failure (HF) based on the latest HF guidelines published in 2022. * N-terminal pro b-type natriuretic peptide (NT-proBNP) \> 1000 pg/mL or Brain Natriuretic Peptide (BNP) \> 250 pg/mL. * Placemen…
Eligibility: Inclusion Criteria: -Hypertension * 18 years old Exclusion Criteria: * Refused to sign informed consent
Eligibility: Inclusion Criteria: * Women * 18-60 years * 5-15 years postpartum Exclusion Criteria: * Atrioventricular block, chronic obstructive pulmonary disease, bronchial asthma * Pregnancy and/or active breastfeeding * Glaucoma disease, epilepsy * In addition for MRI: metal implants, e…
What's being tested:
PROCEDURE: Low Energy SLT
PROCEDURE: Standard Energy SLT
Eligibility: Inclusion Criteria: 1. Age 18 or older and in good health 2. Each eye with one of the following qualifying diagnoses (diagnoses may differ between eyes): 1. High-risk ocular hypertension (OHT): IOP \> 21 mmHg without glaucomatous optic neuropathy (excavation, diffuse or foca…
What's being tested:
OTHER: WB-EMS
OTHER: Control
Eligibility: Inclusion Criteria: * Grade 1 hypertension: systolic 140 and/or diastolic 90 mmHg * overweight or obese (body mass index \> 25 kg/m2) Exclusion Criteria: * blood pressure-lowering pharmacologic therapy. * WB-EMS application and regular resistance exercise training * Conditions…
What's being tested:
OTHER: There are no interventions for this study
Eligibility: Inclusion Criteria: * Female, aged 18 years or above * Willing and able to give informed consent for participation in the study * Able to read and understand written and spoken English to comprehend study materials and give informed consent * Non-pregnant women in good general h…
What's being tested:
OTHER: Intervention arm: expectant management if sFlt-1/PlGF<38
OTHER: Standard care: elective delivery at 37 weeks of gestation
Eligibility: Inclusion Criteria: * Age ≥18 years * Singleton pregnancy * Preeclampsia without severe features according to the ACOG definition * Antegrade diastolic flow in the umbilical artery Doppler * Gestational age between 36+0 and 38+6 weeks of gestation * Gestational age confirmed by…
Eligibility: Inclusion Criteria: * Fulfilment of the 2013 American College of Rheumatology/European Alliance of Associations for Rheumatology (ACR/EULAR) SSc classification criteria * Fulfilment of the 2022 hemodynamic definition of PAH (mean pulmonary arterial pressure (mPAP) \>20 mmHg, pul…
What's being tested:
PROCEDURE: various types of angle interventions
Eligibility: Inclusion Criteria: * Glaucoma patients eligible for standalone or combined angle intervention surgeries, such as LPI, LPIP, goniosynechialysis, trabeculotomy alone or combined with surgical iridectomy or phacoemulsification and intraocular lens implantation; * Patients capable…
What's being tested:
OTHER: Rehabilitation Training
Eligibility: Inclusion Criteria: 1. Patients who suffered from pre-capillary PAH (mPAP ≥ 20 mmHg, PVR \> 2 Woods unit, PAWP ≤ 15 mmHg) confirmed by right heart catheterisation. 2. Patients who are in the status of WHO-FC I-III. 3. Patients between 18 and 75 years old 4. Female subjects are n…
What's being tested:
BEHAVIORAL: Lifestyle counseling and coaching
Eligibility: Inclusion Criteria: * Program admittance will be restricted to patients with 2+ diagnosed diseases that have sufficient evidence for the efficacy of exercise therapy (obesity, hyperlipidemia, metabolic syndrome, polycystic ovarian syndrome, type II diabetes, hypertension, corona…
Showing 1–20 of 1,179 results
Trial data sourced from
ClinicalTrials.gov (U.S. National Library of Medicine). Data may be delayed. Verify enrollment status directly with the research team.