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Copd Trials
440 recruiting trials found
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🏢Sponsor: Rennes University Hospital
📍Locations: Rennes, Brittany Region, France
🎂Age: 18 Years
📅Started: 2021-11-20
What's being tested:
OTHER: Hypnosis + NIV
OTHER: NIV
Eligibility: Pre-inclusion criteria * Man or woman, aged 18 or over, admitted to medical intensive care * Glasgow score = 15 * Patient with acute respiratory failure decompensating COPD and/or having obesity with a body mass index (BMI) greater than 30 * Patient having given free, informed a…
🏢Sponsor: Institut de Recerca Biomèdica de Lleida
📍Locations: Lleida, Catalonia, Spain · Lleida, Spain
🎂Age: 40 Years – 75 Years
📅Started: 2025-10-01
What's being tested:
BEHAVIORAL: Interdisciplinary intervention
Eligibility: Inclusion Criteria: * Adults aged 40 to 75 years. * Confirmed medical diagnosis of chronic obstructive pulmonary disease (COPD) of moderate to severe severity, based on clinical evaluation and pulmonary function testing. * Clinically stable for at least 4 weeks following the las…
🏢Sponsor: VA Office of Research and Development
📍Locations: Detroit, Michigan, United States
🎂Age: 60 Years
📅Started: 2020-12-01
What's being tested:
DEVICE: Positive airway pressure
OTHER: Conservative care (control arm)
Eligibility: Inclusion Criteria: * OSA with moderate-to-severe disease, AHI 20 per hour by in-lab polysomnography with concomitant moderate-severe COPD based on pulmonary function tests (PFTS) and with past significant history (\>10 pack-years) of smoking * Male or female gender * Age greate…
🏢Sponsor: Saglik Bilimleri Universitesi
📍Locations: Istanbul, Turkey (Türkiye)
🎂Age: 40 Years
📅Started: 2024-05-01
What's being tested:
OTHER: CONTROL
DEVICE: PEP DEVICE
DEVICE: HFCWO DEVICE
Eligibility: Inclusion Criteria: * Being classified as GOLD stage 3 or 4 based on spirometric evaluation in the medical history. * Having a hospital admission within the specified time frame, evaluated by a pulmonary specialist, and admitted to the pulmonary diseases service with a diagnosis…
🏢Sponsor: Pulmair Medical, Inc.
📍Locations: Limoges, France · Groningen, Netherlands
🎂Age: 22 Years
📅Started: 2026-02-04
What's being tested:
DEVICE: Implantable pulmonary stent
Eligibility: Inclusion Criteria: 1. Signed Informed Consent 2. Diagnosis of COPD/emphysema 3. At least 22-years of age 4. 18 ≤ BMI ≤ 32 5. 6-minute walk Distance of between 100 - and 400 meters 6. Stable disease with less than 10-mg prednisone (or equivalent) daily 7. Non-smoking for 4-month…
🏢Sponsor: AstraZeneca
📍Locations: Aparecida de Goiânia, Brazil · Bahia, Brazil · Belém, Brazil
🎂Age: 18 Years
📅Started: 2025-01-31
Eligibility: Inclusion Criteria: * Patients of both sexes, aged 18 years or older, with confirmed COPD according to GOLD 2024: previous or current exposure and spirometry (FEV1/FVC =2 or CAT \>=10); or * GOLD E (\>=2 moderate or 1 severe exacerbation - hospitalization); or * GOLD 3 and 4 (FE…
🏢Sponsor: Necmettin Erbakan University
📍Locations: Konya, Turkey (Türkiye)
🎂Age: 18 Years
📅Started: 2023-02-15
What's being tested:
OTHER: health education
OTHER: Mobile application (Creating a WhatsApp group):
OTHER: Telephone interview:
Eligibility: Inclusion Criteria: * Being diagnosed with stage 4 (group D) COPD according to GOLD criteria * Being 18 years or older, * Having a video computer, tablet or phone, * Having an internet connection at home or on the phone, * Residing in the city centre of Konya, * Not having a com…
🏢Sponsor: University of Leicester
📍Locations: Leicester, Leicestershire, United Kingdom
🎂Age: 40 Years
📅Started: 2023-11-22
Eligibility: Phase 1: Inclusion Criteria: * Willing and able to provide informed consent for participation in the research. * The patient has a confirmed diagnosis of COPD using spirometry (based on GOLD criteria (Agustí et al., 2023). * Male or female, aged 40+ years * Able to communicate…
🏢Sponsor: Kirsehir Ahi Evran Universitesi
📍Locations: Kırşehir, Center, Turkey (Türkiye)
🎂Age: 18 Years – 85 Years
📅Started: 2023-11-01
What's being tested:
OTHER: Education and message
Eligibility: Inclusion Criteria: * Diagnosed with COPD for the last 1 year * Hospitalized for at least 3 days, * Voluntary patients Exclusion Criteria: * Under 18 years old * Over 85 years old * Those with chronic fatigue syndrome * Those with severe heart failure * Those who had surgery i…
🏢Sponsor: GlaxoSmithKline
📍Locations: Manchester, United Kingdom
🎂Age: 18 Years
📅Started: 2018-04-15
Eligibility: Inclusion Criteria: * Subjects who were randomized to treatment in the original SLS studies * Subjects who are able to, and choose to, provide written consent for the additional information to be collected. Exclusion Criteria: * Subjects who were lost to follow-up/moved away,…
🏢Sponsor: University of Virginia
📍Locations: Charlottesville, Virginia, United States
📅Started: 2025-01-14
Eligibility: Inclusion Criteria: Post-Bronchodilator FEV1/FVC \<.80 * Race demographics of the recruitment area reflect the population of the Charlottesville Metropolitan Statistical Area (MSA). * Due to underrepresentation in local demographics, special effort (via targeted advertising) wi…
🏢Sponsor: William Poncin, PT, PhD
📍Locations: Brussels, Brussels Capital, Belgium
🎂Age: 40 Years
📅Started: 2024-04-15
What's being tested:
BEHAVIORAL: ELTGOL_Physio
BEHAVIORAL: ELTGOL_Auto
DEVICE: PEP
Eligibility: Inclusion Criteria: * Healthy subjects: No acute or chronic respiratory disease, normal lung function, non-smoker. * Patients with COPD: forced expiratory volume at one second (FEV1) ≤ 80% predicted value, in stable state. Exclusion Criteria: * Healthy subjects: obesity (BMI \…
🏢Sponsor: Skane University Hospital
📍Locations: Karlskrona, Blekinge County, Sweden · Örebro, Sweden
🎂Age: 18 Years
📅Started: 2024-06-10
What's being tested:
DEVICE: Added high-flow oxygen therapy
OTHER: Standard care
Eligibility: Inclusion Criteria: * Age 40 years or older * Ongoing LTOT: prescribed for at least 15 hours per day; and since at least 28 days as registered in Swedevox * COPD or ILD as main underlying reason for LTOT * Oxygen concentrator as stationary oxygen source in the home including nig…
🏢Sponsor: VA Office of Research and Development
📍Locations: Aurora, Colorado, United States · Decatur, Georgia, United States · Boston, Massachusetts, United States
🎂Age: 35 Years – 89 Years
📅Started: 2024-04-01
What's being tested:
DRUG: Tadalafil
DRUG: Placebo
Eligibility: Inclusion Criteria: 1. Outpatients with COPD, defined as airflow limitation with post-bronchodilator obstruction on baseline visit spirometry, identified by FEV1/FVC \< 70% or \< the lower limit of normal (5th percentile of a normal population based on Global Lung Function Initi…
🏢Sponsor: University of Pittsburgh
📍Locations: Pittsburgh, Pennsylvania, United States
🎂Age: 21 Years
📅Started: 2000-08
Eligibility: Inclusion Criteria: * Patients would be required to have COPD based on at least one of the following: clinical history, pulmonary function results, or radiographic results. Exclusion Criteria: * none
🏢Sponsor: Umeå University
📍Locations: Hasselt, Diepenbeek, Belgium · Umeå, Sweden
🎂Age: 60 Years
📅Started: 2023-11-09
What's being tested:
OTHER: Exercise training on a stationary bicycle
Eligibility: The inclusion criteria are: 1. 60 years of age or older 2. Independent in activities of daily living 3. For people with COPD: Symptomatic (COPD assessment test \[CAT\] ≥10 or modified Medical Research Council dyspnea scale \[mMRC\] ≥2) or not being regularly physically active at…
🏢Sponsor: Aarhus University Hospital
📍Locations: Aarhus, Denmark
🎂Age: 18 Years
📅Started: 2023-11-27
Eligibility: Inclusion Criteria: 1. Patients selected to receive treatment with endobronchial valves 2. Signed informed consent Exclusion Criteria: 1. Neuromuscular disease interfering with diaphragm function 2. Pleural effusion at time of preoperative or 90-days postoperative ultrasound
🏢Sponsor: Seattle Institute for Biomedical and Clinical Research
📍Locations: Minneapolis, Minnesota, United States · Portland, Oregon, United States · Charleston, South Carolina, United States
📅Started: 2023-05-15
What's being tested:
OTHER: Population-health management
Eligibility: Inclusion Criteria: * Participants may be PCP physicians and advance practice providers (APP) practicing at participating sites, and their patients who are diagnosed with or treated for COPD based on the following criteria: 1. Recent discharge from hospital for COPD exacerbat…
🏢Sponsor: Peking University Third Hospital
📍Locations: Beijing, Beijing Municipality, China
🎂Age: 35 Years
📅Started: 2024-05-01
What's being tested:
OTHER: previous pulmonary tuberculosis
Eligibility: Inclusion Criteria: * patients who have dyspnea, chronic cough or sputum production and have definite airflow limitation with a post-bronchodilator forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) \<0.7; * in stable condition; * aged 35 years or older Exc…
🏢Sponsor: University of Cape Town
📍Locations: Observatory, WC, South Africa
🎂Age: 18 Years – 65 Years
📅Started: 2020-07-14
What's being tested:
DRUG: Atorvastatin 40mg
DRUG: Placebo oral tablet
Eligibility: Inclusion Criteria 1. Has completed the written informed consent process prior to undergoing any pre-screening or screening evaluations and willing to undergo HIV testing 2. Age 18 to 65 years with body weight from 50 kg to 90 kg 3. Clinical response to TB treatment and sputum c…
Showing 1–20 of 440 results
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Trial data sourced from ClinicalTrials.gov (U.S. National Library of Medicine). Data may be delayed. Verify enrollment status directly with the research team.