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Asthma Trials
377 recruiting trials found
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🏢Sponsor: University Hospital, Lille
📍Locations: Lille, France
🎂Age: 18 Years – 75 Years
📅Started: 2023-02-02
Eligibility: Inclusion Criteria: * Age between 18 and 75 years at the time of inclusion * Asthma diagnosed for at least one year including a history of 1. FEV1 and/or FVC reversibility of more than 12% and than 200 ml documented in the patient's record 2. OR FEV1 variability of more tha…
🏢Sponsor: Chiesi Farmaceutici S.p.A.
📍Locations: Dagenham, United Kingdom
🎂Age: 18 Years – 75 Years
📅Started: 2025-12-17
What's being tested:
DRUG: CHF5993 pMDI with HFA-152a
DRUG: CHF5993 pMDI with HFA-134a
DRUG: CHF718 pMDI with HFA-134a
Eligibility: Inclusion Criteria: * Male and female adults (18 ≤ age ≤ 75 years) with a diagnosis of Asthma for at least 6 months prior to screening and with diagnosis before the age of 50 years; * Non-smokers, ex-smokers; * Body mass index: within the range of 18.0 to 35.0 kg/m2 inclusive; *…
🏢Sponsor: Children's National Research Institute
📍Locations: Washington D.C., District of Columbia, United States
🎂Age: 6 Years – 17 Years
📅Started: 2022-05-01
What's being tested:
DRUG: Omalizumab
DRUG: Placebo
Eligibility: Inclusion Criteria at Study Entry: Participants must meet the following: 1. Parent or guardian must be able to understand and provide informed consent in English and participants ≥7 must be able to provide assent 2. 6-17 years, inclusive at time of screening 3. Physician-diagno…
🏢Sponsor: Novartis Pharmaceuticals
📍Locations: Daegu, Dalseo Gu, South Korea · Wŏnju, Gangwon-do, South Korea · Bucheon-si, Gyeonggi-do, South Korea
🎂Age: 18 Years – 100 Years
📅Started: 2022-05-09
What's being tested:
OTHER: Enerzair 150/50/80 μg
OTHER: Enerzair 150/50/160 μg
Eligibility: Inclusion Criteria: 1. Adult patients (≥18 years of age) with a physician's diagnosis of asthma, who are prescribed Enerzair inhalation capsule (indacaterol acetate/ glycopyrronium bromide/mometasone furoate; 150/50/80, 150/50/160 μg) via Breezhaler, as per the approved label in…
🏢Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
📍Locations: Amsterdam, Netherlands · Groningen, Netherlands
🎂Age: 18 Years
📅Started: 2024-04-09
What's being tested:
PROCEDURE: Bronchial thermoplasty
Eligibility: Inclusion Criteria: * adult (\>18 years) * severe uncontrolled asthma (defined as ACQ above 1.5) despite optimal medical therapy (GINA treatment step 5; alternative diseases excluded, therapy compliance and adequate inhalation technique confirmed) * 1 or more trials of treatment…
🏢Sponsor: Novartis Pharmaceuticals
📍Locations: Rousse, Bulgaria · Sevlievo, Bulgaria · Sofia, Bulgaria
🎂Age: 6 Years – 11 Years
📅Started: 2022-08-29
What's being tested:
DRUG: Glycopyrronium bromide 25ug
DRUG: Placebo
DRUG: Glycopyrronium bromide 12.5ug
Eligibility: Inclusion Criteria: * Confirmed diagnosis of asthma for at least 6 months * Signed informed consent by parent(s)/legal guardian(s) and assent by the pediatric participant (depending on local requirements) * Participant on stable dose of inhaled low-to-medium dose ICS with one ad…
🏢Sponsor: Taichung Veterans General Hospital
📍Locations: Taichung, Taiwan
🎂Age: 18 Years
📅Started: 2023-11-11
What's being tested:
BIOLOGICAL: Biological Treatment for severe asthma patients
Eligibility: Inclusion Criteria: * Provision of informed consent prior to any study specific procedures. * Patient should be reviewed as well as confirmed by the National Health Insurance Administration (NHIA) or by the study board member as a Severe Asthma case. * Female and male aged over…
🏢Sponsor: Prof. Dr. Jörg Leuppi
📍Locations: Liestal, Basel-Landschaft, Switzerland · Bern, Switzerland · Chur, Switzerland
🎂Age: 1 Year
📅Started: 2019-05-13
Eligibility: Inclusion Criteria: * In- and outpatients * Age ≥ 0 year * Informed consent as documented by signature Adults: "Asthma which requires treatment with guidelines suggested medications for GINA steps 4-5 asthma: * High level therapy: 1. high dose ICS with ≥ 1000 μg beclometha…
🏢Sponsor: Imperial College London
📍Locations: London, United Kingdom
🎂Age: 1 Year – 5 Years
📅Started: 2024-02-01
What's being tested:
PROCEDURE: Bronchoscopy, with bronchoalveolar lavage and endobronchial biopsy
DIAGNOSTIC_TEST: Skin prick test
DIAGNOSTIC_TEST: Finger prick blood test
Eligibility: Inclusion Criteria: Aim 1, 2 and 3: * Children aged 1-5 years * More than 2 hospitalisations for acute wheeze in the last year or * At least 1 admission requiring high dependency unit or intravenous bronchodilator therapy in the last year. Aim 1 only: \- children undergoing c…
🏢Sponsor: Kymera Therapeutics, Inc.
📍Locations: Upland, California, United States · Miami, Florida, United States · Tampa, Florida, United States
🎂Age: 18 Years – 75 Years
📅Started: 2026-01-28
What's being tested:
DRUG: KT-621
OTHER: Placebo
Eligibility: Inclusion Criteria: * Must be 18 years old (or the legal age of consent in the jurisdiction in which the study is taking place) to 75 years of age, inclusive, at the time of signing the ICF. * Must have a physician diagnosis of asthma for at least 1 year prior to the Screening v…
🏢Sponsor: University of Massachusetts, Worcester
📍Locations: Worcester, Massachusetts, United States
🎂Age: 5 Years – 14 Years
📅Started: 2024-04-04
What's being tested:
OTHER: Asthma Link
OTHER: Enhanced Usual Care
Eligibility: STUDY INCLUSION/EXCLUSION CRITERIA: Child Inclusion Criteria: * Meet the eligibility criteria for Asthma Link (as described below) * Enrolled in Asthma Link (if randomized to the Asthma Link Condition) * Able and willing to provide informed assent Child Exclusion Criteria: *…
🏢Sponsor: Eli Lilly and Company
📍Locations: Tempe, Arizona, United States · Newport Beach, California, United States · Northridge, California, United States
🎂Age: 18 Years – 75 Years
📅Started: 2025-10-22
What's being tested:
DRUG: Brenipatide
DRUG: Brenipatide
DRUG: Placebo
Eligibility: Inclusion Criteria: * Physician-diagnosed asthma who have received a physician-prescribed asthma controller medication for at least 12 months prior to screening visit. * Participants must have an asthma control questionnaire-6 (ACQ-6) score of ≥1.5 on 2 out of 3 visits before ra…
🏢Sponsor: Boston Children's Hospital
📍Locations: Boston, Massachusetts, United States
🎂Age: 10 Years
📅Started: 2025-12-15
What's being tested:
DEVICE: Smart Inhaler Monitoring Platform for Asthma Management
Eligibility: Inclusion Criteria: 1. Youth or adult with a diagnosis of persistent asthma by a physician. 2. Evidence of uncontrolled asthma as defined by an FEV1/FVC ratio of less than 80% by an asthma provider within the past 3 months, all while on controller asthma therapy. 3. Females or m…
🏢Sponsor: University Hospital, Lille
📍Locations: Lille, France
🎂Age: 18 Years
📅Started: 2020-07-20
What's being tested:
GENETIC: Biobanking with genetic analysis
OTHER: SF-12 questionnaire
Eligibility: Inclusion Criteria: * Patient followed for their IMID in one of the departments of the Lille University Hospital participating in the study (dermatology, internal medicine, neurology, pneumology and rheumatology) * Social insured * Have the capacity to understand the study requi…
🏢Sponsor: AstraZeneca
📍Locations: Wilmington, Delaware, United States
🎂Age: 18 Years
📅Started: 2025-07-09
What's being tested:
OTHER: None (Observational study)
Eligibility: Inclusion Criteria: * Patients with at least one prescription record (based on NDC or healthcare common procedure coding system \[HCPCS\] codes) of Airsupra (for Airsupra arm) or albuterol (for selected albuterol comparator arm) since January 2023 * Patients with an asthma indic…
🏢Sponsor: GlaxoSmithKline
📍Locations: Manchester, United Kingdom
🎂Age: 18 Years
📅Started: 2018-04-15
Eligibility: Inclusion Criteria: * Subjects who were randomized to treatment in the original SLS studies * Subjects who are able to, and choose to, provide written consent for the additional information to be collected. Exclusion Criteria: * Subjects who were lost to follow-up/moved away,…
🏢Sponsor: AstraZeneca
📍Locations: Astrakhan, Russia · Blagoveshchensk, Russia · Bryansk, Russia
📅Started: 2024-06-27
Eligibility: Inclusion Criteria: 1. Age ≥ 18 years at the time of inclusion; 2. Signed and dated written informed consent in accordance with ICH GCP and local law prior to inclusion in the study; 3. Patients with diagnosis of uncontrolled mild and moderate asthma (according to Global Initiat…
🏢Sponsor: The Institute of Molecular and Translational Medicine, Czech Republic
📍Locations: Olomouc, Czechia
📅Started: 2015-05-01
What's being tested:
DIAGNOSTIC_TEST: Collection of breath condensate
Eligibility: Inclusion Criteria: * Children/adults with moderate or IgE mediated asthma * Children/adults with cystic fibrosis * Healthy control children/adults without lung disorders Exclusion Criteria: \-
🏢Sponsor: Stanford University
📍Locations: New York, New York, United States · New York, New York, United States
🎂Age: 18 Years
📅Started: 2019-09-24
Eligibility: Inclusion Criteria: * Age 18 or older * English-speaking * Prior diagnosis of asthma per the electronic health record * Experiencing an ED visit for asthma as per ED clinician * Medically appropriate for survey study as determined by treating ED clinician
🏢Sponsor: Hacettepe University
📍Locations: Ankara, Turkey (Türkiye)
🎂Age: 18 Years – 65 Years
📅Started: 2024-03-01
What's being tested:
OTHER: Exercise capacity
Eligibility: Inclusion Criteria: * No respiratory, cardiovascular and metabolic diseases * Regular non-smoker Exclusion Criteria: * Non-consenting * Pregnant women
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Trial data sourced from ClinicalTrials.gov (U.S. National Library of Medicine). Data may be delayed. Verify enrollment status directly with the research team.