What's being tested:
BEHAVIORAL: HeartGPS
Eligibility: Inclusion Criteria 1. Pregnant person carrying a fetus diagnosed with single ventricle congenital heart disease (CHD). 2. Single ventricle CHD diagnosis between 16 and 30 weeks gestation. 3. Singleton pregnancy. 4. Pregnant person is planning to continue with the pregnancy. 5. P…
What's being tested:
BEHAVIORAL: Dream Yoga Inspired Intervention
BEHAVIORAL: Sleep Health Enhancement Program (SHEP)
Eligibility: Inclusion Criteria: * Individuals interested in participating will be screened for eligibility through a Qualtrics survey, a Score between 5-21 points in GAD-7. Healthy, English-speaking adults (at least 18 years old) with high dream recall (at least 1/week). Exclusion Criteri…
What's being tested:
DEVICE: Implantation of a DBS therapy system
Eligibility: Inclusion Criteria: * a score of 25 or higher on the Yale-Brown Obsessive Compulsive Scale * previous failure to respond to at least two medication trials with serotonin reuptake inhibitors at or, if tolerated, beyond the FDA maximum recommended dose for a minimum duration over…
What's being tested:
BEHAVIORAL: The EMPOWER Program
Eligibility: Inclusion Criteria: Parents will be eligible to participate if: 1. Their child has anxiety and/or Obsessive-Compulsive Disorder (OCD) (either subclinical or clinical), as determined by an initial screening 2. Their child is between the age of 5 and 12 years-old 3. Parents are E…
What's being tested:
DIETARY_SUPPLEMENT: Sarmentosin - L- theanine
OTHER: Resistance Training
DIETARY_SUPPLEMENT: Placebo Supplement
Eligibility: Inclusion criteria 1. Perimenopausal women between 40 - 55 years 2. Not currently engaging in consistent structured resistance training (defined as \>3 resistance training sessions per week for 4 consecutive weeks, in the past six months). 3. Not on any HRT or hormonal contracep…
What's being tested:
DRUG: Fluoxetine
DRUG: Dextromethorphan
Eligibility: Inclusion Criteria: * Diagnosis of obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), illness anxiety disorder (IAD) or somatic symptom disorder (SSD) * Living within California * Capacity to provide informed consent Exclusion Criteria: * Current bipolar diso…
What's being tested:
BEHAVIORAL: Emotion Regulation Therapy via Telehealth
Eligibility: Inclusion Criteria: * Between the ages of 18 and 65 * Fluent in English (and therefore able to provide consent) * Currently living in New York State * Access to at least one device with internet and video-conferencing capabilities * High self-reported worry, rumination, and/or s…
What's being tested:
DRUG: Nociceptin Receptor Antagonist
DEVICE: Aversive stimuli
Eligibility: Inclusion criteria for MDD/anxiety disorder group: * DSM-5 diagnostic criteria for MDD, Generalized Anxiety Disorder, Social Phobia, Panic Disorder, Post Traumatic Stress (diagnosed using the SCID-5) * Written informed consent * For MDD subjects, a baseline Hamilton Depression R…
What's being tested:
DRUG: Ranquilon
DRUG: Afobazole
Eligibility: Inclusion Criteria: 1. Males and females aged 18 to 70 years; 2. Written informed consent form in accordance with current legislation; 3. Patients with anxiety and established diagnoses based on ICD-10 criteria: neurasthenia (F48.0) or adjustment disorder (F43.2); 4. Anxiety sev…
What's being tested:
BEHAVIORAL: Endorphin Massage
Eligibility: Inclusion Criteria: * Being admitted to the hospital for cesarean section * Being willing to participate in the research Exclusion Criteria: * Having psychiatric illness * native language not Turkish
What's being tested:
BEHAVIORAL: Cognitive Remediation Training
OTHER: Control Group
Eligibility: Inclusion Criteria * Age 18 to 45 years * Able to speak and read French fluently * Access to a computer with a camera and a secure Internet connection * Access to a private space for assessment and intervention sessions * Available for the complete treatment protocol * Confirmed…
What's being tested:
PROCEDURE: RESC
OTHER: NSCS
Eligibility: Inclusion Criteria: * Planned cardiac surgery with extracorporeal circulation * Pre operatory anxiety : STAI-E score \>30 or Visual Analogue Scale Anxiety \>6 Exclusion Criteria: * Urgent surgery * Atrial fibrillation * Impossibility to answer to STAI-E or VAS * Use of alterna…
What's being tested:
DEVICE: Active cTBS
DEVICE: Inactive/Sham cTBS
BEHAVIORAL: Imaginal exposure
Eligibility: Inclusion Criteria: * Mild traumatic brain injury (mTBI) defined in accord with the World Health Organization criteria in the last 12 months * age 18-65 at the time of the mTBI * high burden of post-concussive symptoms defined as a score \>=20 on the Rivermead Post-Concussion Sy…
What's being tested:
BEHAVIORAL: No Dog Present
BEHAVIORAL: Dog is Present
Eligibility: Inclusion Criteria: * presenting to clinic for elbow pin removal post elbow fracture surgery Exclusion Criteria: * dog allergy * fear of dogs
What's being tested:
BEHAVIORAL: Mindfulness Intervention for Emotional Distress (self-guided version)
Eligibility: Inclusion Criteria: * experiencing emotional distress such as depression or anxiety (Kessler-10 score \> 21) Exclusion Criteria: * prior experience with mindfulness meditation * current self-harm or suicidal risk * bipolar disorder or schizophrenia * history of substance abuse…
What's being tested:
DRUG: fsCBD Cannabidiol
DRUG: Placebo
DRUG: bsCBD Cannabidiol
Eligibility: Inclusion Criteria: 1. Able to provide informed consent 2. Aged ≥25 years at Visit 1 (Baseline) 3. Have a diagnosis of any solid tumor type and is currently undergoing or has undergone either curative or palliative treatment in the past 18 months 4. Currently experiencing sympto…
What's being tested:
DRUG: Dupilumab
Eligibility: Inclusion Criteria: * Participants who have moderate to severe AD with signs and symptoms of anxiety and/or depression. * Participants who initiate dupilumab therapy within 30 days of enrolment, based on the treating physician's decision, independently of study participation * P…
What's being tested:
BEHAVIORAL: Education
OTHER: Excercise
OTHER: Placebo
Eligibility: Inclusion Criteria: * Subjects aged between 18 and 65 years * Subjects with non-specific neck pain at the time of the intervention, scoring at least 3 on the NPRS scale. Exclusion Criteria: * Pregnancy * Severe illnesses: diabetes, cancer, neurological conditions, depression,…
What's being tested:
BEHAVIORAL: Collaborative Care
Eligibility: Inclusion Criteria: * 18+ * Current membership and active on patient portal * Depression Diagnosis in the prior year * Overdue for PHQ9 Screening based on the following criteria: * High Risk: Last PHQ9 screener was completed greater than 4 months ago AND total Score is greate…
What's being tested:
DEVICE: Active transcranial direct current stimulation
DEVICE: Sham transcranial direct current stimulation
Eligibility: Inclusion Criteria: * All Participant Inclusion Criteria would include: 1. 18 years of age or older 2. speak English fluently, and 3. able to provide written and verbal informed consent. * Obsessive-compulsive disorder (OCD) Inclusion Criteria would include: 1. meet cr…
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Trial data sourced from
ClinicalTrials.gov (U.S. National Library of Medicine). Data may be delayed. Verify enrollment status directly with the research team.