Eligibility: Inclusion Criteria: 1. Male and female adults aged ≥55 and ≤85 years at the time of written consent 2. Subjects with a Korean Mini-Mental State Examination (K-MMSE) score of 20 to 28 3. Have a global Clinical Dementia Rating (CDR) score of 0.5 to 1 and a CDR Memory Box score of…

Eligibility: Inclusion Criteria: A subject with MCI with a likelihood of underlying AD pathophysiology must meet the following criteria: * Established diagnosis of MCI due to AD with a likelihood according to NIA-AA criteria (Albert et al., 2011). * A score of stage three on the Global Dete…

Eligibility: Inclusion Criteria: 1. self-reported Native Hawaiian or other Pacific Islander ancestry; 2. ages 50+ but not older than 75 (optimal age range for preventing future dementia in people with cognitive impairment, above 75 is not likely to benefit from this study given their advance…

Eligibility: Inclusion Criteria: * Healthy older adults will show cognitive performance within 1.0 SD for age \& education adjusted norms on a neuropsychological test battery * Mild cognitive impairment (MCI) participants will show performance on delayed recall or one more or more other cogn…

Eligibility: Inclusion Criteria: * 50 years old or older. * 20 adults with no mild-cognitive impairment * 20 adults with mild-cognitive impairment * 20 adults with Alzheimer's disease/ dementia. * participant or the participant's legally authorized representative must be able to read…

Eligibility: Inclusion Criteria: 1. Patients in all cohorts will be male or female adults from 40 to 85 years of age. 2. Participants must be informed of the investigational nature of this study and be willing to provide written informed consent and participate in this study in accordance wi…

Eligibility: Inclusion criteria: * Age 65+ years old * Any age and ethnicity. * With or without, or at risk of mild to moderate dementia and healthy controls. * Availability of a study partner (informant) who has contact with the patient at least once a week (this can also be the surrogate/L…

Eligibility: General Inclusion Criteria: * Native Spanish speaker. * Agree to the examination procedures and tests. * Ability to involve a close family member or friend for functional evaluation. * Normal or corrected-to-normal color vision. * No medical condition requiring chronic systemic…

Eligibility: Inclusion Criteria: 1. Age ≥65 years 2. Education ≥7 years 3. Fluency in the German language 4. Completed neuropsychological assessment (max. 3 months before data collection of CogCheck) 5. Informed consent signed 6. Clinical course based on caregiver information and neuropsycho…

Eligibility: Inclusion Criteria: * Willingness and ability to complete all aspects of the study (including MRI, clinical genotyping, and PET imaging or CSF as applicable) for the duration of the study. The participant should be capable of completing assessments either alone or with the help…

Eligibility: Inclusion Criteria: * Adults aged 18 years or older * One of the following: * Clinical diagnosis of Alzheimer's disease or related dementia * Being a caregiver to individuals with clinical diagnosis of Alzheimer's disease or related dementia * Able to read and speak English…

Eligibility: Inclusion Criteria: 1. patients with AD whose clinical dementia rating (CDR) is \> 1 2. Spouses of Patients in the above group Or 3. Healthy adult unrelated to groups 1 and 2, with no history of dementia And 4. Regardless of the grouping, the prospective subject must be between…

Eligibility: Inclusion Criteria: * Speaks/reads English * Resident of Virginia, North Carolina, Maryland, West Virginia, Tennessee, Kentucky or Washington, D.C. * Age 18+ * Is either the grandchild, sibling, niece/nephew, step-kin, adult child or spouse of the person living with dementia * I…

Eligibility: Inclusion Criteria: 1. Residents aged 30 to 79, whose residence is consistent with their registered permanent residence location; 2. Residents who voluntarily participate in the project, agree to the collection of their biological information, and sign the informed consent form;…

Eligibility: Inclusion Criteria: * 50+ Years of age * Male or Female * At enhanced risk of Alzheimers Disease (defined as family history of AD, 1st degree family member) * Overweight or Obese (BMI≥25kg/m\^2) * Habitually consume suboptimal diets such as typical Western Diet (i.e., high in an…

Eligibility: Inclusion Criteria: 1. Diagnosis of AD according to the 2024 National Institute on Aging and Alzheimer's Association criteria. 2. Male or female, aged 55 - 85 years. 3. MMSE 20-28 at screening and baseline. 4. CDR global score=0.5 or 1, with memory box score at least 0.5 at scre…

Eligibility: Inclusion Criteria: * Ability of the participant and/or his/her legally authorized representative to understand the purpose and risks of the study, to provide signed and dated informed consent, and to authorize the use of confidential health information. * Ability to speak and r…

Eligibility: Inclusion Criteria: * postmenopausal women * 40 - 65 years Exclusion Criteria: * Longer than 10 years in menopause * thyroid dysfunction * hypertension * medical history of psychiatric comorbidity * Alcohol and/or drug abuse * medical history of neurologic symptoms with cognit…

Eligibility: Inclusion Criteria: 1. The Sponsor will rely on NIA-AA Alzheimer's Disease Diagnostic Guidelines for Early Symptomatic Alzheimer's Disease (AD) with a 20-30 MMSE score, Clinical Dementia Rating (CDR) global score of 0.5 or 1, and impaired memory performance below an education ad…

Eligibility: Inclusion Criteria: 1. Provide written informed consent, signed, and dated by the participant and study partner, or by the participant's legally authorized representative if applicable, according to local regulations for the ICF and, if applicable, country specific ICFs. 2. Part…